Caffeine good for the liver
Monday, August 19, 2013
Your morning latte might do more than give you a buzz — Singapore
researchers found it could reduce liver fat in people with non-alcoholic fatty
liver disease (NAFLD).
NAFLD is becoming increasingly common in the West, thanks to
rising diabetes and obesity rates.
The liver should not contain fat, however people who are obese or
have diabetes can get fat deposits on the liver, which can lead to
inflammation, swelling and tenderness,or even fibrosis or cirrhosis.
When studying mice, the researchers from Duke University found
that caffeine stimulated the fat stores in the liver and decreased fatty liver
in mice that were fed a high fat diet.
They suggest drinking four cups of tea or coffee a day could stop
NAFLD getting worse in humans.
"This is the first detailed study of the mechanism for
caffeine action on lipids in liver and the results are very interesting,"
said study leader Paul Yen.
"Coffee and tea are so commonly consumed and the notion that
they may be therapeutic, especially since they have a reputation for being
'bad' for health, is especially enlightening."
The downside with caffeine consumption is that it can stimulate
the heart and also disrupt sleep if consumed late in the day, so the
researchers said their study could lead to the development of a drug that
utilises caffeine properties to help the liver, but does not have the same side
effects.
Professor Joseph Proietto, a diabetes and obesity expert from the
University of Melbourne, has advised that the study is promising.
"The study is in mice so it's difficult to translate a dose
you might need to have the affect in humans," he said.
"What it now requires is a randomised controlled trial in
humans. Until we have that, then we can't advise people to start drinking lots
of coffee."
Professor Prioetto said the best way to correct fatty liver is to
lose weight.
The study was published in the
journal Hepatology.